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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAB2
All Species:
9.09
Human Site:
S474
Identified Species:
20
UniProt:
Q9UQC2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQC2
NP_036428.1
676
74458
S474
R
A
G
D
N
S
Q
S
V
Y
I
P
M
S
P
Chimpanzee
Pan troglodytes
XP_525517
686
74573
D468
S
D
S
I
A
S
E
D
S
C
V
P
M
N
P
Rhesus Macaque
Macaca mulatta
XP_001093917
677
74423
S475
R
A
G
D
N
S
Q
S
V
Y
I
P
M
S
P
Dog
Lupus familis
XP_542285
762
83533
S560
R
A
G
D
N
S
Q
S
V
Y
I
P
M
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1S8
665
73190
M468
S
Q
S
V
Y
I
P
M
S
P
G
P
H
H
F
Rat
Rattus norvegicus
Q9EQH1
665
73310
M468
S
Q
S
A
Y
I
P
M
G
P
G
P
H
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513247
815
89872
A561
L
T
E
P
I
Q
E
A
N
Y
V
P
M
T
P
Chicken
Gallus gallus
XP_001234549
681
75233
N473
K
A
N
D
N
A
Q
N
L
Y
I
P
M
S
P
Frog
Xenopus laevis
NP_001089201
691
76011
M491
Q
V
P
P
P
A
H
M
G
F
R
S
S
P
K
Zebra Danio
Brachydanio rerio
XP_692935
666
73590
P469
Y
I
P
M
S
P
G
P
H
H
F
D
F
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZZ9
878
95517
A620
R
H
C
Y
T
N
A
A
P
T
K
M
E
G
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.5
98.8
83
N.A.
91.7
91.2
N.A.
33.2
78.1
38.6
63
N.A.
20.9
N.A.
N.A.
N.A.
Protein Similarity:
100
73.7
99.5
85.9
N.A.
93.6
93.7
N.A.
46.5
87.6
56
74.4
N.A.
37.8
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
100
100
N.A.
6.6
6.6
N.A.
26.6
66.6
0
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
100
N.A.
6.6
6.6
N.A.
53.3
93.3
20
13.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
37
0
10
10
19
10
19
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
10
0
37
0
0
0
10
0
0
0
10
0
0
0
% D
% Glu:
0
0
10
0
0
0
19
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
10
0
10
0
19
% F
% Gly:
0
0
28
0
0
0
10
0
19
0
19
0
0
10
10
% G
% His:
0
10
0
0
0
0
10
0
10
10
0
0
19
19
0
% H
% Ile:
0
10
0
10
10
19
0
0
0
0
37
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% K
% Leu:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
28
0
0
0
10
55
0
0
% M
% Asn:
0
0
10
0
37
10
0
10
10
0
0
0
0
10
10
% N
% Pro:
0
0
19
19
10
10
19
10
10
19
0
73
0
19
55
% P
% Gln:
10
19
0
0
0
10
37
0
0
0
0
0
0
0
0
% Q
% Arg:
37
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
28
0
28
0
10
37
0
28
19
0
0
10
10
37
0
% S
% Thr:
0
10
0
0
10
0
0
0
0
10
0
0
0
10
0
% T
% Val:
0
10
0
10
0
0
0
0
28
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
19
0
0
0
0
46
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _